A. S. Bommarius, B. R. Riebel
Hardcover, 611 Pages
First Edition, 2004
The whole range of biocatalysis, from a firm grounding in theoretical concepts to in-depth coverage of practical applications and future perspectives.
"Biocatalysis" is an interesting and outstanding text book for the topic biocatalysis. The authors treat the topic integrativly: Biochemistry, organic synthesis, molecular biology, kinetics and engineering are lit up. This basic approach makes the book interesting, particularly for students, because the most important basics are covered by this book.
The book clearly addresses itself to future engineers and biotechnologists, who will find very interesting data of important industrial synthesis with enzymes in this book. For others the book offers, however, a very interesting reading pleasure and some additional knowledge, because chapters for the use of enzymes as detergants, additives in animal feed and also which important enzymes are already used today in the industrial production (including very surprising space-time yields) are absolutely worth reading.
Basics of cell biology and also about bio computer science, enzyme kinetics and many more areas are rounding off the overall view successfully. The book is indeed an assistance for engineers, who want to specialize themselves in bio catalysis and want to succeed in the surrounding field between biology, biochemistry and chemistry.
PART I: FUNDAMENTALS AND BASIC TOOLS
Position of biocatalysis within biotechnology
Characterization of a (bio-)catalyst
Isolation and preparation of microorganisms
Molecular biology tools for biocatalysis
Enzyme reaction engineering
Applications of enzymes as bulk actives: detergents, textile, pulp and paper, animal feed
Applications of enzymes as catalyst:Chemicals, fine chemicals, food, pharmaceuticals
PART II: ADVANCED TOOLS
Biotechnological processing steps for enzyme manufacture
Methods for the investigation of proteins
Applications of recombinant DNA technology: Directed evolution
Biocatalysis in non-conventional media
Pharmaceutical applications of biocatalysis
Systems biology for biocatalysis
PART III: APPLICATIONS
Evolution of biocatalytic function
Stability of proteins
Design of biocatalytic processes
Comparison of biocatalysts with homogeneous and heterogeneous chemical catalysts
New functions through application of bioinformatics
Genomics and proteomics: applications