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The Chemistry of Heterocycles. Structure, Reactions, Syntheses, and Applications

Theophil Eicher, Siegfried Hauptmann

Paperback, 570 Pages
First Edition, 12 June 2003
ISBN: 3-527-30720-6


The second edition of this “classic” among textbooks on heterocycle industry. Here, Theophil Eicher and Siegfried Hauptmann, both renowned authors of many successful such works, present all the important aspects of this fascinating field in clear manner.

Completely revised.

- Enlarged
- Numerous Q&As help readers to deepen their knowledge
- Covers the very latest topics, such as metal-catalyzed coupling reactions
- Systematic substance nomenclature
- Comprehensive overview of all the important substance classes

A must-have for advanced students of organic chemistry as well as for chemists looking for a quick overview of the field.

Editorial Review

Heterocycles - organic, cyclic compounds with at least one heteroatom - occur in natural products and are the building blocks of new, active pharmaceutical ingredients. They are catalyst ligands and components of materials. Heterocycles with a high ring tension are used as synthons, such as epoxides and aziridines.

As building blocks, they make it possible to introduce physical and chemical properties into molecules that would not be realizable with pure carbon chemistry. The spectrum ranges from electron-poor pyridines to electron-rich pyrroles. Furans show different properties than pyrroles and thiophenes.

"The Chemistry of Heterocycles" is a mixture between a textbook and a reference work. It accompanies students in specialization blocks on the subject of heterocycles, because in addition to the most important compounds, it also contains nomenclature rules. The book offers the researcher a very good overview with the chemical and physical properties (synthesis, stability, d 1H-NMR, 13C, pKa) of over 100 heterocycles and information on the most important literature references. "The Chemistry of Heterocycles" invites you to browse, but also helps to find suitable heterocycles - be it compounds that are easy to synthesize or have required structural features.


The Structures of Heterocyclic Compounds
Systematic Nomenclature of Heterocyclic Compounds
Three-Membered Heterocycles
Four-Membered Heterocycles
Five-Membered Heterocycles
Six-Membered Heterocycles
Seven-Membered Heterocycles
Larger Rings
Problems and Their Solutions
General Subject Index
Index of Named Reactions