Categories: Organic Chemistry >> Bio >> Natural Products

Essentials of Carbohydrate Chemistry and Biochemistry

Description

Concise yet complete, this is a succinct introduction to the topic, covering both basic chemistry as well as such advanced topics as high-throughput analytics and glycomics -- in one handy volume. This improved and expanded 3rd edition features all-new material on combinatorial synthesis of carbohydrates and carbohydrate biodiversity, and each chapter now contains study questions for self-learning and classroom teaching. Didactically written by an experienced lecturer and graduate student advisor, the text is backed by practical examples and more than 150 study questions tailored to students' needs.

Editorial Review

In recent years, investigations of the biological molecules in cell walls have resulted in a virtual explosion in the area of carbohydrate chemistry. It is here that glycoproteins interact with other molecules and pathogens, which is why they are of particularly great interest to research. The structural diversity of glycoconjugates, which is highly species specific, presents formidable challenges in this work, often requiring specialists who have the corresponding synthesis and analytical know-how.

"Essentials of Carbohydrate Chemistry and Biochemistry" presents the fundamentals and important research areas within carbohydrate chemistry in a compact yet well-structured form. Since the book is anchored in the fundamentals of organic chemistry, advanced students will find the text to be quite easily understandable overall. The spectrum of topics is broad, but the reader can be confident that the individual subjects have been handled well. Lindhorst succeeds in presenting the most important themes in an intelligent context, and his book provides students with a readily usable toolkit to employ in later research.

Furthermore, the book includes a cornucopia of synthesis procedures for protecting groups, couplings, or for the application of carbohydrates as chiral pool materials, so that practitioners in this field of endeavor will gladly refer back to "Essentials of Carbohydrate Chemistry and Biochemistry" on occasion. This book is thus a highly recommended buy, both for students who have a serious interest in biomolecules, their functions and syntheses, as well as for research and development chemists who must familiarize themselves with the fundamentals, or who have need of the synthesis procedures.

Contents

Introduction to Carbohydrates
Structure of Saccharides
Protecting Groups for Carbohydrates
Important modifications and functionalizations of the sugar ring
O-Glycoside Synthesis
Structure and Biosynthesis of Glycoconjugates
Glycobiology
Purification and Analysis of Carbohydrates
The Literature of Carbohydrate Chemistry