M. T. Reetz, B. List, S. Jaroch, H. Weinmann
Hardcover, 200 Pages
First Edition, 2007
Due to the emergence of organocatalysis as a highly active and very exciting field of research both in academia and the life sciences industry, an Ernst Schering Research Foundation Symposium was organized in 2007 to bring together the scientific leaders in this field and to discuss the basics and current progress of organocatalysis and its application in drug discovery. Various aspects of organocatalysis are addressed in this volume, covering a broad range of synthetic transformations such as functional group interconversions as well as CC- and CX-bond formations and their applications in natural product and drug syntheses. In addition, the design and scope of various catalyst systems are discussed, from small molecules, to peptides, to genetically engineered enzymes.
The book "Organocatalysis" seems at first glance to be rather plain and utilitarian. The subtitle "Symposium Proceedings" suggests that the content will also be underwhelming, but readers with an interest in organocatalysis should take a closer look. The contributions originate from well-known German research groups that took part in the Ernst Schering Foundation Symposium; remarkably, one doesn’t get the feeling of reading through procedures or abstracts, but rather of having in hand a qualitatively first-class book.
In addition to a very good introduction, the first chapter by Benjamin List contains detailed explanations, mechanisms and a good overview of the numerous areas in which they work, since his research group is occupied nearly full-time with organocatalysis. Given the scope and interests of the authors, this work clearly cannot cover the entire potential of organocatalysis, but the majority of the authors present their research work in a lively and in-depth style. Thus, the wealth of advice on strategy and optimization possibilities make this book an exceptionally fascinating read.
As a result, "Organocatalysis" is recommended as a “must-read” for all who have an interest in the current research themes of this field, and who prefer a handy summary that will provide them first-hand with many new ideas.
Polymer-supported Organic Catalysts