2-Hydroperoxy-4,6-diphenyl-1,3,5-triazine (Triazox)
2-Hydroperoxy-4,6-diphenyl-1,3,5-triazine (Triazox) is a bench-stable solid, that can easily be synthesized from cheap starting materials. Triazox is a relatively mild epoxidation reagent, that produces a nonacidic triazinone byproduct.
Recent Literature
A bench-stable, solid triazine-based oxidizing reagent,
2-hydroperoxy-4,6-diphenyl-1,3,5-triazine (Triazox) can be synthesized from
inexpensive starting materials. This reagents has been used for epoxidation of
alkenes possessing acid-sensitive functionalities in good to excellent yields.
The accompanying nonacidic triazinone coproduct can be easily removed by
filtration.
K. Yamada, Y. Igarashi, T. Betuyaku, M. Kitamura, K. Hirata, K. Hioki, M.
Kunishima, Org. Lett.,
2018, 20, 2015-2019.
