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Acetone, 2-Propanone

Recent Literature


Oxidative methyl esterification of primary alcohols and diols with methanol in the presence of acetone as a hydrogen acceptor was successfully achieved under catalysis of an iridium complex combined with 2-(methylamino)ethanol (MAE).
N. Yamamoto, Y. Obora, Y. Ishii, J. Org. Chem., 2011, 76, 2937-2941.


A Ni-catalyzed intermolecular coupling of primary alcohols and organotriflates provides ketones in the presence of acetone. Two competitive oxidation processes, that generate aldehyde in situ via hydrogen transfer oxidation or (pseudo)dehalogenation pathways, are followed by a Ni-catalyzed carbonyl-Heck process.
T. Verheyen, L. van Turnhout, J. K. Vandavasi, E. S. Isbrandt, W. M. De Borggraeve, S. G. Newman, J. Am. Chem. Soc., 2019, 141, 6869-6874.


An effective protocol for Oppenauer (OOP) oxidation of alcohols under mild conditions with t-BuCHO as hydride acceptor was developed. The highly active aluminium catalyst allowed even the oxidation of terpenoids and stereoids with acetone as the hydride acceptor.
S. S. Kim, H. C. Jung, Synthesis, 2003, 2135-2137.


A base-free rhodium-catalyzed Mizoroki-Heck reaction of potassium aryltrifluoroborates with alkenes in the presence of acetone as green "oxidant" constitutes an interesting alternative to conventional olefinations using aryl halides thanks to the ready availability of organoboranes.
S. S. Kim, H. C. Jung, Synthesis, 2003, 2135-2137.