Diethyl allyl phosphate, allyl diethyl phosphate (DEAP)
Diethyl allyl phosphate is a hydrogen acceptor, that can for example be used in Pd-catalyzed oxidations.
Recent Literature
Allyl-nickel catalysis enables α,β-dehydrogenation of carbonyl compounds. In
addition, an oxidative cycloalkenylation reaction provides access to
bicycloalkenones with fused, bridged, and spirocyclic ring systems using
unactivated ketone and alkene precursors.
D. Huang, S. M. Szewczyk, P. Zhang, T. R. Newhouse, J. Am. Chem. Soc.,
2019,
141, 5669-5674.
The use of allyl-palladium catalysis enables a one-step α,β-dehydrogenation of
ketones via their zinc enolates. The optimized protocol utilizes commercially
available Zn(TMP)2 as base and diethyl allyl phosphate as oxidant,
operates under salt-free conditions, and tolerates a diverse scope of
cycloalkanones.
D. Huang, Y. Zhao, T. R. Newhouse, Org. Lett.,
2018, 20, 684-687.
