Ferric Chloride, Iron(III) Chloride, Fe(Cl)3
Ferric chloride is a mild oxidizing agent.
Recent Literature
Pd, Ru, and Fe catalysis enable a general synthesis of 2-substituted pyrroles in
overall good yields with only water and ethene as side-products. The route
starts with two subsequent Pd-catalyzed monoallylations of amines with allylic
alcohols. Ru-catalyzed ring-closing metathesis performed on the diallylated
amines provides pyrrolines in excellent yields. By addition of ferric chloride,
a selective aromatization was achieved.
A. Bunrit, S. Sawadjoon, S. Tšupova, P. J. R. Sjöberg, J. S. M. Samec, J. Org. Chem.,
2016,
81, 1450-1460.
Anhydrous FeCl3 oxidizes potassium thiocyanate to the corresponding
radical and promotes subsequent addition to nucleophilic olefins to produce
dithiocyanate derivatives under mild conditions with excellent yields and
chemoselectivities. The use of ferric chloride makes this method simple,
convenient and practical.
J. S. Yadav, B. V. S. Reddy, M. K. Gupta, Synthesis,
2004, 1983-1986.
