A silver-catalyzed double-decarboxylative protocol enables an efficient and pratical construction of chalcone derivatives via cascade coupling of substituted α-keto acids with cinnamic acids under mild and environmentally benign aqueous conditions.
N. Zhang, D. Yang, W. Wei, L. Yuan, F. Nie, L. Tian, H. Wang, J. Org. Chem., 2015, 80, 3258-3263.
An efficient Na2S2O8-promoted radical coupling of tertiary cycloalkanols with alkynyl hypervalent iodide reagents provides β-, γ- and δ-alkynylated ketones via C-C bond cleavage. This tandem ring-opening/alkynylation procedure offers mild conditions and wide substrate scope.
S. Wang, L.-N. Guo, H. Wang, X.-H. Duan, Org. Lett., 2015, 17, 4798-4801.
A Pd-catalyzed C-H bond activation/C-C bond formation/cyclization cascade process enables the synthesis of quinolinone derivatives from simple anilines as the substrates. This method provides access to quinolinone-containing alkaloids and drug molecules.
J. Wu, S. Xiang, J. Zeng, M. Leow, X.-W. Liu, Org. Lett., 2015, 17, 222-225.
An iron-catalyzed oxidative cyclization of 1-acyl-3-(phenyl)thioureas in the presence of sodium persulfate gave various N-benzothiazol-2-yl-amides selectively in good yields through C(sp2)-H functionalization and C-S bond formation.
J. Wang, Y. Zong, X. Zhang, Y. Gao, Z. Li, G. Yuo, Z. Quan, X. Wang, Synlett, 2014, 25, 2143-2148.