A Pd-catalyzed reaction of water with a diboron compound as the reductant produces clean hydrogen gas under ambient reaction conditions. The B2Pin2-H2O system enables a selective hydrogenation of olefins in the presence of a palladium catalyst.
D. P. Ojha, K. Gadde, K. R. Prabhu, Org. Lett., 2016, 18, 5062-5065.
A B2Pin2-assisted copper-catalyzed semihydrogenation of alkynes provides various alkenes in good to excellent yields with Z-selectivity under mild reaction conditions. The present protocol enabled convenient synthesis of deuterium-substituted Z-alkenes using readily available ethanol-d1 as the deuterium source.
H. Bao, B. Zhou, H. Jin, Y. Liu, J. Org. Chem., 2019, 84, 3579-3589.
The combination of B2pin2 and KOtBu enables a chemoselective, metal-free reduction of aromatic nitro compounds to the corresponding amines in very good yields in isopropanol. The reaction tolerates various reducible functional groups.
H. Lu, Z. Geng, J. Li, D. Zou, Y. Wu, Y. Wu, Org. Lett., 2016, 18, 2774-2776.