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Chemicals >> Reducing Agents

Methylhydrazine

see also: hydrazine


Recent Literature


The use of methylhydrazine as a reducing agent in combination with an easily synthesized and robust Co catalyst and a polar protic solvent enables a chemoselectively reduction of nitroarenes to arylamines in excellent yields.
D. I. Ioannou, D. K. Gioftsidou, V. E. Tsina, M. G. Kallitsakis, A. G. Hatzidimitriou, M. A. Terzidis, P. A. Angaridis, I. N. Lykakis, J. Org. Chem., 2021, 86, 2895-2906.


A selective photoinduced reduction of nitroarenes to N-arylhydroxylamines proceeds with a broad scope, excellent functional-group tolerance, and high yields in the absence of catalyst or additives and uses only light and methylhydrazine.
M. G. Kallitsaki, D. I. Ioannou, M. A. Terzidis, G. E. Kostakis, J. N. Lykakis, Org. Lett., 2020, 22, 4339-4343.