Potassium borohydride, Potassium tetrahydroborate
Name Reactions
Recent Literature
A catalytic enantioselective 1,2-reduction of enones with potassium
borohydride is catalyzed by a chiral N,N'-dioxide-Sc(III) complex
catalyst under mild reaction conditions. A number of optically active allylic
alcohols were obtained in very good enantioselectivities with nearly
quantitative yields.
P. He, X. Liu, H. Zheng, W. Li, L. Lin, X. Feng, Org. Lett., 2012,
14, 5134-5137.
In a reduction of nitroarenes using KBH4 and I2, BI3
is generated in situ and was shown to be the active reductant. Conditions were
optimized for BI3 generation and then applied to a wide range of
nitroarenes, including traditionally challenging substrates. The method
constitutes a practical reduction option which produces low-toxicity boric acid
and potassium iodide upon workup.
A. Ćorković, T. Chiarella, F. J. Williams, Org. Lett., 2023, 25,
8787-8791.
