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Chemicals >> Reducing Agents

sec-Butanol, 2-Butanol

see also: isopropanol

Recent Literature

An intermolecular Ni-catalyzed reductive coupling of aryl iodides and isatins provides 3-hydroxyoxindoles in the presence of sec-butanol as a mild stoichiometric reductant. This formal 1,2-addition reaction is facilitated by a 1,5-diaza-3,7-diphosphacyclooctane (P2N2) ligand.
A. Nasim, G. T. Thomas, J. S. Ovens, S. G. Newman, Org. Lett., 2022, 24, 7232-7236.