Sodium aminodiboranate, NaADBH
NaNH2(BH3)2 offers a reducing capacity between NaBH4 and LiAlH4. The reagent is a promising agent for hydroboration due to its stability and ease of handling. For example carboxylic acids can selectively be reduced to primary alcohols.
Recent Literature
Sodium aminodiboranate (NaNH2(BH3)2, NaADBH) is a promising reducing agent
for hydroboration because of its stability and easy handling. Hydroboration
reactions of carboxylic acids using NaADBH provide primary alcohols with
excellent yields and good selectivity. This alternative synthetic approach
tolerates a wide range of functional groups.
J. Wang, M.-Y. Ju, X. Wang, Y.-N. Ma, D. Wei, X. Chen, J. Org. Chem., 2021, 86,
5305-5316.
Sodium aminodiboranate (NaNH2(BH3)2, NaADBH) is
a member of the borane family with superior performance in chemoselective
reduction. NaADBH can rapidly reduce aldehydes and ketones to the corresponding
alcohols in high efficiency and selectivity under mild conditions. Steric and
electronic effects have only a limited influence.
J. Wang, Y. Guo, S. Li, X. Chen, Synlett, 2021, 32,
1104-1108.
