Organic Chemistry Portal
Chemicals >> Reducing Agents

Tetrahydroxydiboron, Bis-Boric Acid, BBA, B2(OH)4

Tetrahydroxydiboron is a reducing agent, that for example slowly produces hydrogen gas in water.

See also: Bis(pinacolato)diboron, Bis(neopentylglycolato)diboron

Recent Literature

A metal-free reduction of nitro aromatics is mediated by tetrahydroxydiboron under mild conditions in water as solvent to provide various aromatic amines with good functional group tolerance and in good yields.
D. Chen, Y. Zhou, H. Zhou, S. Liu, Q. Liu, K. Zhang, Y. Uozumi, Synthesis, 2018, 50, 1765-1768.

A copper-catalyzed one-pot reaction of 2-nitrobenzonitriles and various carbonyl compounds in the presence of diboronic acid as a reductant provides 2,3-dihydroquinazolin-4(1H)-ones with good functional-group tolerance in good yields under mild conditions.
Q. Liu, Y. Sui, Y. Zhang, K. Zhang, Y. Chen, H. Zhou, Synlett, 2020, 31, 275-279.