Trimethoxysilane (TMS)
Recent Literature
A transition-metal-free catalytic hydrosilylation based on t-BuOK (5 mol
%) and (MeO)3SiH or (EtO)3SiH allows the reduction of
tertiary amides to their corresponding enamines with high selectivity in very
good yields.
A. Volkov, F. Tinnis, H. Adolfsson, Org. Lett., 2014,
16, 680-683.
A Ni-catalyzed radical transfer strategy enables an efficient, modular,
asymmetric hydrogenation and hydroalkylation of alkenyl fluorides with primary,
secondary, and tertiary alkyl halides under mild conditions. The transformation
provides facile access to structurally complex secondary and tertiary α-fluoro
amide products from readily available starting materials with excellent
substrate compatibility.
F. Chen, Q. Zhang, Y. Li, Z.-X. Yu, L. Chu, J. Am. Chem. Soc.,
2024, 146, 11418-11431.
A Mn-catalyzed N-F bond activation enables a visible-light-promoted
generation of amidyl radicals from N-fluorosulfonamides. In the presence
of a cheap silane, (MeO)3SiH as hydrogen-atom donor and F-atom
acceptor, intra- and intermolecular hydroaminations of alkenes, two-component
carboamination of alkenes, and even three-component carboamination of alkenes
can be realized.
Y.-X. Ji, J. Li, C.-M. Li, S. Qu, B. Zhang, Org. Lett., 2021, 23,
207-212.
