See also: triethylphosphite
The use of chiral α-alkyl N-tert-butanesulfinyl imidates and α-aryl N′-tert-butanesulfinyl amidines enables a diastereoselective α-hydroxylation using molecular oxygen. The aza-enolates generated from deprotonation of the imidates/amidines react with O2 followed by transformation into α-hydroxylation products in the presence of trimethyl phosphite as reductant.
P.-J. Ma, H. Liu, Y.-J. Xu, H. A. Aisa, C.-D. Lu, Org. Lett., 2018, 20, 1236-1239.
Trialkyl phosphites mediate a convenient, efficient, and inexpensive deoxygenation of 1,2,3-triazine 1-oxide for the synthesis of 1,2,3-triazine derivatives in high yield. Triethyl phosphite is more reactive than trimethyl phosphite, and both phosphites form their corresponding phosphates in these reactions.
G. Rivera, L. De Angelis, A. Al-Sayyed, S. Biswas, H. Arman, M. P. Doyle, Org. Lett., 2022, 24, 6543-6547.