Organic Chemistry Portal
Reactions >> Name Reactions

Further Information

Related Reactions
Corey-Kim Oxidation
Jones Oxidation
Swern Oxidation

Dess-Martin Oxidation

The Dess-Martin Periodinane (DMP), a hypervalent iodine compound, offers selective and very mild oxidation of alcohols to aldehydes or ketones.

The oxidation is performed in dichloromethane or chloroform at room temperature, and is usually complete within 0.5 - 2 hours. Products are easily separated from the iodo-compound byproduct after basic work-up.

Mechanism of the Dess-Martin Oxidation

Recent Literature

Acceleration of the Dess-Martin Oxidation by Water
S. D. Meyer, S. L. Schreiber, J. Org. Chem., 1994, 59, 7549-7552.

Recyclable 2nd generation ionic liquids as green solvents for the oxidation of alcohols with hypervalent iodine reagents
J. S. Yadav, B. V. S. Reddy, A. K. Basak, A. V. Narsaiah, Tetrahedron, 2004, 60, 2131-2135.

Heteroaromatic Synthesis via Olefin Cross-Metathesis: Entry to Polysubstituted Pyridines
T. J. Donohoe, J. A. Basutto, J. F. Bower, A. Rathi, Org. Lett., 2011, 13, 1036-1039.