Categories: C-B Bond Formation > Synthesis of boronic acids and boronates >
Synthesis of α-aminoboronates
Recent Literature
An efficient visible-light-induced decarboxylative borylation of α- and
β-amino redox-active esters with bis(catecholato)diboron, followed by
transamination with 1,8-diaminonapthalene (DANH2) provide a series of
boronamides in good yields in a one-pot procedure. The photochemical can also be
conducted under flow conditions.
A. Serafino, H. Pierre, F. Le Vaillant, J. Boutet, G. Guillamot, L. Neuville.,
G. Masson, Org. Lett., 2023, 25,
9249-9254.
Related
A boryl-directed intermolecular C-H amination of allyl N-methyliminodiacetyl
boronates (B(MIDA)s) and propargylic B(MIDA)s provide α-amino boronates with an
exceptionally high level of site-selectivity. A wide variety of highly
functionalized secondary and tertiary α-amino boronates are formed in very good
yields under mild reaction conditions.
Y. Liu, Z.-H. Chen, Y. Li, J. Qian, Q. Li, H. Wang, J. Am. Chem. Soc.,
2022, 144, 14380-14387.
A boryl-directed intermolecular C-H amination of allyl N-methyliminodiacetyl
boronates (B(MIDA)s) and propargylic B(MIDA)s provide α-amino boronates with an
exceptionally high level of site-selectivity. A wide variety of highly
functionalized secondary and tertiary α-amino boronates are formed in very good
yields under mild reaction conditions.
Y. Liu, Z.-H. Chen, Y. Li, J. Qian, Q. Li, H. Wang, J. Am. Chem. Soc.,
2022, 144, 14380-14387.