Categories: C-C Bond Formation > Oxygen-containing molecules >
Synthesis of esters, carbonates and related compounds
Recent Literature
Chiral α-(carbamoyloxy)alkylcopper reagents, prepared using Hoppe's sBuLi/(-)-sparteine
methodology and subsequent transmetalations with ZnCl2 and CuCN,
reacted with various electrophiles to give enantiomerically pure alcohols after
deprotection.
J. P. N. Papillon, R. J. K. Taylor, Org. Lett., 2002, 4,
119-122.
A bimetallic titanium complex [(salen)TiO]2 catalyzes the asymmetric addition of ethyl cyanoformate to aldehydes leading
to cyanohydrin carbonates with high enantiomeric excesses.
Y. N. Belokon, A. J. Blacker, L. A. Clutterbuck, M. North, Org. Lett.,
2003,
5, 4505-4507.