Categories: C-C Bond Formation > Oxygen-containing molecules, Nitrogen-containing molecules > Carbonyl compounds >

Synthesis of β-amino ketones, aldehydes and derivatives

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Recent Literature

Upon exposure of enamides to aldehydes in the presence of a chiral NHC catalyst, C-C bond formation provides N-protected amines, bearing a quaternary carbon center, in good yields and with high enantioselectivities.
J. Wu, C. Zhao, J. Wang, J. Am. Chem. Soc., 2016, 138, 4706-4709.