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Synthesis of Alkanoyl and Aroyl Cyanides
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A practical cyanation of aroyl chlorides was performed in DMF at room
temperature with 0.2 equivalent of a non-toxic cyanide source, 3 mol% AgI, 4
mol% PEG-400, and 3 mol% KI as the catalyst system. The corresponding aroyl
cyanides were prepared in good yields.
Z. Li, S. Shi, J. Yang, Synlett, 2006,
2495-2497.