Categories: C-C Bond Formation > Nitrogen-containing molecules >
Synthesis of β-Amino Acids and Derivatives
Related: |
|
|
Recent Literature
A general alkylamination of vinylarenes and an unprecedented
diastereoselective anti-carboamination of unsaturated esters provide amines
and unnatural β-amino acids. This alkylamination is enabled by an iron catalyst
and alkyl diacyl peroxides, that serve as both alkylating reagents and internal
oxidizing agents.
B. Qian, S. Chen, T. Wang, X. Zhang, H. Bao, J. Am. Chem. Soc., 2017,
139, 13076-13082.