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Synthesis of 1,2-difluoroalkanes
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A catalytic, vicinal difluorination of olefins displays broad functional group
tolerance, using inexpensive p-iodotoluene as the catalyst. Preliminary
efforts toward the development of an enantioselective variant are reported.
I. G. Molnár, R. Gilmour, J. Am. Chem. Soc., 2016,
138, 5004-5007.