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Synthesis of hydroxamates (Weinreb amides)


Recent Literature

Trimethoxyphenyliodonium(III) acetate serves as an efficient arylation reagent for N,O-protected hydroxylamines, generating N-methoxysulfonylanilines derivatives in the absence of transition metal catalysts. This amination reaction is compatible with several protecting groups, including Troc, Cbz, Boc, benzyl, acetyl, and silyl groups.
K. Kikushima, A. Morita, E. E. Elboray, T. Bae, N. Miyamoto, Y. Kita, T. Dohi, Synthesis, 2022, 54, 5191-5202.