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Synthesis of imides


Protecting Groups


Recent Literature

A manganese pincer complex catalyzes a dehydrogenative coupling of diols and amines to form cyclic imides. The reaction forms hydrogen gas as the sole byproduct, making the overall process atom economical and environmentally benign.
N. Angel Espinosa-Jalapa, A. Kumar, G. Leitus, Y. Diskin-Posner, D. Milstein, J. Am. Chem. Soc., 2017, 139, 11722-11725.

An economical and practical method for the synthesis of a wide range of imide derivatives has been developed by using inexpensive and readily available reagents under mild conditions.
P. Y. Reddy, S. Kondo, T. Toru, Y. Ueno, J. Org. Chem., 1997, 62, 2652-2654.

A Lewis acid catalyzed and solvent free procedure for the preparation of imides from the corresponding anhydrides uses TaCl5-silica gel as Lewis acid under microwave irradiation.
S. Chandrasekhar, M. Takhi, G. Uma, Tetrahedron Lett., 1997, 38, 8089-8092.