Categories: C-N Bond Formation >
Synthesis of imides
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Recent Literature
A direct coupling of NH-amides with methylarenes under iodine/aqueous TBHP
conditions enables a metal-free synthesis of imides. The optimized conditions
worked also very well with benzaldehydes and benzyl alcohol and furnished the
corresponding imides in good to excellent yields.
H. Aruri, U. Singh, S. Kumar, M. Kushwaha, A. P. Gupta, R. A. Vishwakarma, P. P.
Singh, Org. Lett.,
2016, 18, 3638-3641.
An iodine-catalyzed oxidative C-H/N-H cross-coupling enables an efficient
construction of α-ketoimides in good to excellent yields from methyl ketones and
benzamidines hydrochloride under metal-free and peroxide-free conditions.
X. Wu, Q. Gao, S. Liu, A. Wu, Org. Lett., 2014,
16, 2888-2891.
