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Synthesis of thiophosphines

Recent Literature


A palladium-catalyzed deformylative P-C cross-coupling reactions of hydroxymethylphosphine derivatives enables a practical and versatile syntheses of tertiary phosphine derivatives. Sequential couplings of orthogonally protected precursors provide a simple and practical route toward a variety of tertiary aryl-substituted phosphine derivatives in any combination.
M. Hayashi, T. Matsuura, I. Tanaka, H. Ohta, Y. Watanabe, Org. Lett., 2013, 15, 628-631.


A catalytic amount of a Brønsted base mediates a stereoselective diphosphination of terminal alkynes with diphosphanes to deliver the corresponding (E)-1,2-diphosphinoethenes in good yields. This reaction offers a good alternative to precedented transition-metal-catalyzed or radical-promoted approaches to the 1,2-diphosphinoethene framework of potent interest in catalysis and coordination chemistry.
Y. Okugawa, K. Hirano, M. Miura, Org. Lett., 2017, 19, 2973-2976.


A stereoselective hydrophosphination reaction of alkynes with diphenylphosphane has been developed. The reaction is mediated by a cobalt catalyst and butyllithium.
H. Ohmiya, H. Yorimitsu, K. Oshima, Angew. Chem. Int. Ed., 2005, 44, 2368-2370.