Categories: C-S Bond Formation >
Synthesis of sulfilimines
The reaction of sulfinimidate esters with Grignard reagents enables the preparation of protected sulfilimines in high yields and with a remarkable structural variability. Moreover, the transformation can be performed in cyclopentyl methyl ether as a green solvent.
M. Andresini, M. Spennachio, M. Colella, G. Losito, A. Aramini, L. Degennaro, R. Luisi, Org. Lett., 2021, 23, 6795-6800.