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Synthesis of sulfoximines


Recent Literature

A sulfur-selective arylation of easily accessible chiral sulfinamides enables an asymmetric synthesis of chiral sulfoximines. The utility of the present method is demonstrated by the asymmetric synthesis of a key intermediate of a COX-2 inhibitor.
Y. Aota, T. Kano, K. Maruoka, J. Am. Chem. Soc., 2019, 141, 19263-19268.