Categories: C=C Bond Formation >
Synthesis of allenes by semireduction
| Related: | ||
 |
 |
 |
 |
||
 |
||
 |
||
 |
Recent Literature
An efficient enantio- and chemoselective copper hydride catalyzed
semireduction of conjugated enynes provides 1,3-disubstituted allenes using
water as the proton source. This protocol tolerates various functional groups including keto, ester, amino, halo, and hydroxyl
groups.
L. Bayeh-Romero, S. L. Buchwald, J. Am. Chem. Soc.,
2019,
141, 13788-13794.