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Categories: CC Bond Formation

Synthesis of α,β-unsaturated compounds


Recent Literature

Optimized conditions for the Wittig reaction of aldehydes with ethyl tribromoacetate and triphenylphosphine allowed the synthesis of α-bromoacrylates with high selectivity. A simple and efficient one-pot procedure was developed for the preparation of various conjugated acetylenic carboxylates in good yields.
J.-G. Kim, D. H. Kang, D. O. Jang, Synlett, 2008, 443-447.