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O-H Bond Formation


Reduction of carbonyl compounds

Reduction of carboxyl compounds to alcohols

Reduction of α,β-unsaturated compounds

Reduction of epoxides

Cleavage of ethers

Cleavage of esters

Cleavage of carbonates

Cleavage of carbamates

Cleavage of silyl ethers

Cleavage of acetals

Cleavage of hemiaminals

Recent Literature

Magnesium in methanol is an effective reagent for the chemoselective reduction of ozonides and other peroxides. Mg/MeOH is significantly more reactive than Me2S or PPh3 and somewhat more reactive than Zn/HOAc.
P. Dai, P. H. Dussault, T. K. Trullinger, J. Org. Chem., 2004, 69, 2851-2852.