Categories: Synthesis of N-Heterocycles, Synthesis of O-Heterocycles >
Synthesis of 1,2,5-oxadiazoles
Recent Literature
1,1'-Carbonyldiimidazole induces the formation of various 3,4-disubstituted
1,2,5-oxadiazoles (furazans) from the corresponding bisoximes at ambient
temperature. This method enables the prepartion of these inherently energetic
compounds at temperatures well below their decomposition points and with
improved functional group compatibility.
A. J. Neel, R. Zhao, Org. Lett.,
2018, 20, 2024-2027.