Organic Chemistry Portal >
Reactions > Organic Synthesis Search

Categories: Synthesis of N-Heterocycles > Lactams

Synthesis of 3,6-dihydro-2-pyridinones

Recent Literature

A palladium-catalyzed carbonylative [5+1] cycloaddition of N-tosyl vinylaziridines with CO provides α,β-unsaturated δ-lactams in dimethylformamide and β,γ-unsaturated δ-lactams in tetrahydrofuran in very good yields.
T. Zhang, S. Wang, D. Zuo, J. Zhao, W. Luo, C. Wang, P. Li, J. Org. Chem., 2022, 87, 10372-10376.