Categories: Synthesis of N-Heterocycles > benzo-fused N-Heterocycles >
Synthesis of phenanthridinones
Recent Literature
Visible light and KOtBu promote a dehydrogenative C-H carbonylative
lactamization of 2-arylanilines with DMF as the sole carbonyl source. The
irreversible release of hydrogen gas drags this reaction to the stable
phenanthridinone products.
Y.-Z. Chen, T.-H. Ding, Q.-Q. Li, J.-P. Qu, Y.-B. Kang, Org. Lett., 2023, 25,
2612-2615.
In a constant-potential electrolysis (CPE) for the synthesis of
phenanthridinones, TBAI plays a dual role as both a redox catalyst and a
supporting electrolyte. This metal and oxidant free reaction proceeds with 100%
current efficiency via an intramolecular C-H activation under mild reaction
conditions and with a short reaction time.
K. Subramanian, S. L. Yedage, K. Sethi, B. M. Bhanage, Synlett, 2021,
32, 999-1003.