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Synthesis of imidazolidines

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Copper efficiently catalyzes a reaction of N-sulfonylaziridines and N-alkylanilines in the presence of tert-butyl hydroperoxide to afford functionalized imidazolidines via nucleophilic ring opening, sp3 C-H functionalization, and C-N bond formation. The protocol can be used for the enantiospecific synthesis of imidazolidines with excellent optical purity.
M. Sengoden, A. Bhowmick, T. Punniyamurthy, Org. Lett., 2017, 19, 158-161.