Categories: Synthesis of N-Heterocycles >
Synthesis of pyrazines
The reactivity of α-imino carbenoids derived from α-diazo oxime ethers with 2H-azirines enables a synthesis of unsymmetrically substituted pyrazines. The reaction provides highly substituted pyrazines in good to excellent yields.
N. S. Y. Loy, S. Kim, C.-M. Park, Org. Lett., 2015, 17, 395-397.